Cardiac Function and Organ Blood Flow at Early Stage Following Severe Burn

Multiple organ dysfunction syndrome (MODS) has been the difficulty in clinical treatment of severe burns. In the 1990s, the incidence rate of MODS was 28.1% in severe burn patients, while the mortality rate was as high as 78%-98% (Huang et al., 1998). MODS was caused by two “attacks": the first attack was the early plasma leakage and the effective circulating blood volume reduction, as resulted in the systemic hypoxic-ischemic damage; the second attack was the invasion of consequent systemic inflammatory response and sepsis on the organs (Sheng, 2002). With enhancement of the clinical treatment of burns, the present point of view argues that the key to prevention of MODS is against the first "attack", ie, to control the burn shock, which can effectively prevent or mitigate the second "attack" to reduce the incidence of MODS (Sheng, 2002).